Opportunity

As part of the Translational DMPK‑PD and Clinical Pharmacology chapter, you will focus on providing the right drug at the right dose to patients safely with an efficacious benefit. You will collaborate closely with therapeutic areas to convert hypotheses into innovative medicines, driving nonclinical strategies to bring forward the best clinical candidates for specific indications.

Impact & Responsibilities

• Strategy & Design:

  Lead drug design and optimization strategies and compound profiling for all DMPK aspects, with a strong focus on target biology validation and translational PK/PD concepts.

• Translational Evaluation:

  Provide support to early discovery teams in the development of translational strategies for the clinical evaluation of target modulation through the application of biochemical and pharmacological considerations.

• Modeling & Simulation (M&S):

  Execute fundamental M&S ...